Definition and prevalence of familial short stature
نویسندگان
چکیده
منابع مشابه
Idiopathic Short Stature: Conundrums of Definition and Treatment
Children with idiopathic short stature (ISS) are statistically defined by height SDS < -2 for their bone age and should be distinguished from children with familial short stature for whom height SDS corresponds to mean parental SDS and from the most common explanation for short stature referred to pediatric endocrinologists, constitutional delay in growth and maturation (CDGM), in which there i...
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Aggrecan, encoded by ACAN, is a major proteoglycan component of the extracellular matrix in the growth plate and articular cartilage. Aggrecan provides the hydrated gel structure important for the load-bearing properties of joints and plays a key role in cartilage and bone morphogenesis. At least 25 pathological ACAN mutations have been identified in patients with highly variable phenotypes of ...
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OBJECTIVE To develop a chart to identify non-familial short stature. DESIGN A height chart that adjusts for maternal, paternal, midparental, or sibling height based on the British 1990 height reference. MAIN OUTCOME MEASURE Height between 2 and 9 years of age. RESULTS The chart identifies children whose height is below the familially adjusted 0.4th centile, assuming a correlation of 0.4 b...
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The aim of the present study was to determine the prevalence of celiac disease in children of short stature and to assess whether some of the routine laboratory examinations performed to determine the cause of short stature could suggest the presence of celiac disease. A total of 106 children of short stature and no gastrointestinal symptoms were studied. An extensive endocrine work-up had been...
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Growth disorders are considered as one of the common complications of thalassemia major patients. The present study was conducted to examine the prevalence of short stature, underweight, and delayed puberty in patients with thalassemia major in Iran. This review study was conducted based on systematic review and meta-analysis protocol (PRISMA) until 2017. To access relevant literature, two res...
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ژورنال
عنوان ژورنال: Italian Journal of Pediatrics
سال: 2021
ISSN: 1824-7288
DOI: 10.1186/s13052-021-01018-3